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Infobits

Welcome to Frosina's Infobits section. Here you will find a wealth of ilittle-known or unusual nformation about Albania and the Albanians!

Ferid Murad: Albanian-American Nobel Prize Winner
Date posted: Friday, August 6, 2004
Author: Murad

Murad Prof. Ferid Murad, born in the US, son of an Albanian moslem immigrant father and an American Baptist mother, was awarded the Nobel prize in Medicine in 1998. He received his M.D. Degree in 1965 from Case Western Reserve University in Cleveland, Ohio, from which he also received a Ph.D. in Pharmacology that same year. Among other awards/honors that Dr. Murad has earned are the Ciba Award - American Heart Assoc. (1988); NIDDK Bd. of Scientific Counselors (1990-1994) (Chairman, 1993-1994); Lasker Award for Basic Research (1996); Member National Academy of Sciences (1997); Member Inst. of Med. National Academy of Sciences (1998). He is the author/co-author of some 334 medical/scientific publications. The following article about Dr. Murad was excerpted from The Jerusalem Post, November 29, 1998:

 

"Dr. Ferid Murad, chairman of the department of integrative biology and pharmacology at the University of Texas (Houston) Medical School, will receive the Nobel prize along with Robert Furchgott of the State University of New York and Louis Ignarro of the University of Californa at Los Angeles. All three, working independently in Texas, California, and New York, have spent decades conducting basic research on nitric oxide (NO). Not only did their discoveries lead to the use of Viagra for treating impotence, they have now found that NO - which in minute quantities acts as the body's most important signaling molecule - is profoundly involved in blood pressure, heart function, infections, lung problems, and the defense of the body against tumors, as well as having the potential to treat disease.

Although his father was an Albanian Moslem and his mother an American Baptist, Murad became an Episcopalian and married Carol, a Presbyterian teacher who is the mother of their five grown children. "My parents had a tiny restaurant in our home town of Whiting, Indiana, and I used to wash dishes and wait on tables to cover the cost of my medical studies. I didn't write down what people ate - I memorized the details as a kind of game, and I think that helped me later in my scientific work."

When Dr. Fathi Arafat, president of the Palestinian Red Crescent, learned that Murad had come to Jerusalem to lecture, he informed his brother, Palestinian Authority chairman Yasser Arafat, who invited Murad to Gaza for a 30-minute weekend meeting.

Murad, whose university is the largest medical research institution in the world, noted that NO has the ability to dilate blood vessels and relax smooth muscle tissue; this led to its application in the anti-impotence pill (Viagra). But he also predicted that NO will be relevent in the fight against cancer, Alzeimer's disease, heart disease and many other conditions. Altho researchers have long known various details about NO, in 1977 Murad discovered that nitroglycarin pills - used by heart patients for a century - work because they release NO. The colorless, odorless gas signals blood vessels to relax, which lowers blood pressure and relieves the pain of angina pectoris. "For years, colleagues said I was crazy to invest so much time and effort in NO," Murad recalled. "But I was certain right from the beginning."

Ironically, Alfred Nobel, the inventor of dynamite (a product in which the explosion-prone nitroglycarin is curbed by being absorbed in a porous soil) became ill with heart disease, and his doctor prescribed nitroglycarin. Nobel refused to take it, knowing that it caused headache and dismissing the possibility that it could eliminate chest pain.

Murad, who works 16 to 18 hours a day, noted that since the Nobel prize announcement, he has been overwhelmed by queries and invitations to collaborate in important research projects. "I used to get 5 or 10 applications a month; now I receive an average of 15 a week. I'm no more brilliant or stupid than I was before the announcement - but now everybody's listening," he said with a smile"."

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